7  Advanced Topics

7.1 Other Sites

Sites that are useful for general background

• Abbott Freestyle Libre Users (Facebook): https://www.facebook.com/groups/748445301888935/

  • Active (20K members) and includes people from Abbott

• Diabettech site: https://www.diabettech.com/freestylelibre/

• QS Guide: Testing Food with Blood Glucose: another nice overview: https://quantifiedself.com/blog/qs-guide-testing-food-with-blood-glucose/

• Quantified Self Conference 2018 had a breakout session: see their notes here: https://forum.quantifiedself.com/t/qs18-links-and-resources/5885/4 which are based on a lengthy May 2017 thread by Gary Wolf in the same forum.

• Freestyle Libre Tips and Hacks: Youtube videos by Nerdabetic

  https://www.youtube.com/watch?v=o7R5Of-iWfk

• Reddit: /r/Diabetes

  • Especially check the thread on “Things you wished you knew about the Freestyle sensors”

7.2 Hardware

7.2.1 Freestyle Libre hardware information

• Freestyle Libre sensor teardown: Blogger Ido Roseman takes one apart, with photos.
• Reddit forum says: “it would appear that Libre sensors use NfcV, while S8 does not support NfcV (ISO 15693) but happily talks over NfcA and NfcB (ISO/IEC 14443). “
• Insulin calculator: settings/professional and password = CAA1C

7.2.2 Freestyle-compatible

Hardware devices that work with the Freestyle Libre. Using an NFC reader that talks directly to the Libre sensor, they send information to a bluetooth phone.

• MiaoMiao Shanghai company $200
• Ambrosia Systems Nightrider: $110 NFC-to-bluetooth device
• Bubblan: Supports All Libre Sensors except US Libre2 version : 139.99€

7.2.3 Other hardware

• Bionous: Seattle-Bellevue company that claims to have a low-cost non-invasive glucose reader (PHWare)
• Jobst Technologies Biosensors: hardware company that sells biosensors that detect glucose.
• http://tula-health.com/content/tech.html is raising money for a non-invasive CGM.
• OnDuo: An open resource doc about Google-Verily and Sanofi’s diabetes program that features CGM.
• Medtronic Guardian: open resource doc about another sensor+phone integrated CGM with prediction capabilities

7.3 Scientific articles

• Journal of Diabetes Science and Technology (2020) concludes that Freestyle Libre 2 performs within 20% of blood values.
• Lancet article (2016) that established the accuracy of the underlying CGM technology
• Glucotypes (2018): Stanford study claims people respond differently to foods
  • See news article summary
  • Upload your data to their online app here: https://abreschi.shinyapps.io/shinySpecClust/
• Personalized Nutrition by Prediction of Glycemic Responses (Cell: Zeevi et al 2015)
  • Highly-cited study showing differences are driven by the microbiome
• “Continuous Gluose Profiles in Healthy Subjects” (2007) study.
• FDA approval document: more details about Freestyle Libre and its authorized uses
  • (see similar approval for Dexcom, a de novo iCGM)
• “Hunting the Deceitful Turkey” 100+ page book about the tech behind non-invasive glucose monitoring

A handy table of CGM clinical trials (via AMJC)

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8 Other Summary Resources

Other places to find more links and other information

Continuous Glucose Monitor page for the open source Loop project.